Dynamin 1 antibody (pSer778)

Catalog No. ABIN296563

This Sheep Polyclonal antibody specifically detects Dynamin 1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow and Chicken.

Quick Overview for Dynamin 1 antibody (pSer778) (ABIN296563)

Target: Dynamin 1 (DNM1)

Reactivity: Human, Mouse, Rat, Dog, Cow, Chicken

Host: Sheep

Clonality: Polyclonal

Conjugate: This Dynamin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Dynamin 1 Antibody

Binding Specificity: pSer778

Specificity: Specific for the ~95k dynamin protein phosphorylated at Ser778. Labels the purified protein phosphorylated in vitro by cdk5 but not by PKC. Does not cross react with other purified substrates of cdk5 (e. g. amphiphysin and synapsin). Immunolabeling is blocked by X-phosphatase treatment.

Purification: Immunoaffinity purified

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phosphoSer778 of rat dynamin.

Application Details

Application Notes: Approved: WB (1:1000)

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 μLof 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for Dynamin 1

Target: Dynamin 1 (DNM1)

Alternative Name: DNM1 / Dynamin

Background: Name/Gene ID: DNM1
Family: Dynamin

Synonyms: DNM1, Dynamin, Dynamin-1, DNM, Dynamin 1

Gene ID: 1759

UniProt: Q05193

Pathways: Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling