CHD3 antibody

Catalog No. ABIN2983311

This Mouse Monoclonal antibody specifically detects CHD3 in WB, IHC, ELISA, FACS and IF/ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for CHD3 antibody (ABIN2983311)

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CHD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-CHD3 Antibody

Immunogen: Purified recombinant fragment of human CHD3 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for CHD3

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Alternative Name: CHD3

Background: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Molecular Weight: 226 kDa

Gene ID: 1107

UniProt: Q12873