SSB antibody (AA 166-408)

Catalog No. ABIN3015265

This Rabbit Polyclonal antibody specifically detects SSB in WB, IHC, IF and IP. It exhibits reactivity toward Human.

Quick Overview for SSB antibody (AA 166-408) (ABIN3015265)

Target: SSB (Sjogren Syndrome Antigen B (SSB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-SSB Antibody

Binding Specificity: AA 166-408

Sequence: KFVETPGQKY KETDLLILFK DDYFAKKNEE RKQNKVEAKL RAKQEQEAKQ KLEEDAEMKS LEEKIGCLLK FSGDLDDQTC REDLHILFSN HGEIKWIDFV RGAKEGIILF KEKAKEALGK AKDANNGNLQ LRNKEVTWEV LEGEVEKEAL KKIIEDQQES LNKWKSKGRR FKGKGKGNKA AQPGSGKGKV QFQGKKTKFA SDDEHDEHDE NGATGPVKRA REETDKEEPA SKQQKTENGA GDQ

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 166-408 of human SSB (NP_003133.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SSB

Target: SSB (Sjogren Syndrome Antigen B (SSB))

Alternative Name: SSB

Background: The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.,SSB,LARP3,La,La/SSB,Epigenetics & Nuclear Signaling,RNA Binding,Immunology & Inflammation,SSB

Molecular Weight: 46 kDa

Gene ID: 6741

UniProt: P05455