RPGR antibody (AA 1-260)

Catalog No. ABIN3015610

The Rabbit Polyclonal anti-RPGR antibody has been validated for WB and IHC. It is suitable to detect RPGR in samples from Human.

Quick Overview for RPGR antibody (AA 1-260) (ABIN3015610)

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPGR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RPGR Antibody

Binding Specificity: AA 1-260

Sequence: MREPEELMPD SGAVFTFGKS KFAENNPGKF WFKNDVPVHL SCGDEHSAVV TGNNKLYMFG SNNWGQLGLG SKSAISKPTC VKALKPEKVK LAACGRNHTL VSTEGGNVYA TGGNNEGQLG LGDTEERNTF HVISFFTSEH KIKQLSAGSN TSAALTEDGR LFMWGDNSEG QIGLKNVSNV CVPQQVTIGK PVSWISCGYY HSAFVTTDGE LYVFGEPENG KLGLPNQLLG NHRTPQLVSE IPEKVIQVAC GGEHTVVLTE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RPGR (NP_001030025.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RPGR

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Alternative Name: RPGR

Background: This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.,RPGR,COD1,CORDX1,CRD,PCDX,RP15,RP3,XLRP3,orf15,Epigenetics & Nuclear Signaling,RNA Binding,Neuroscience,RPGR

Molecular Weight: 52 kDa/70 kDa/83 kDa/90 kDa/113 kDa/127 kDa

Gene ID: 6103

UniProt: Q92834