IDS antibody (AA 34-290)

Catalog No. ABIN3015634

The Rabbit Polyclonal anti-IDS antibody has been validated for WB, IHC and IF. It is suitable to detect IDS in samples from Human.

Quick Overview for IDS antibody (AA 34-290) (ABIN3015634)

Target: IDS (Iduronate 2-Sulfatase (IDS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IDS Antibody

Binding Specificity: AA 34-290

Sequence: TDALNVLLII VDDLRPSLGC YGDKLVRSPN IDQLASHSLL FQNAFAQQAV CAPSRVSFLT GRRPDTTRLY DFNSYWRVHA GNFSTIPQYF KENGYVTMSV GKVFHPGISS NHTDDSPYSW SFPPYHPSSE KYENTKTCRG PDGELHANLL CPVDVLDVPE GTLPDKQSTE QAIQLLEKMK TSASPFFLAV GYHKPHIPFR YPKEFQKLYP LENITLAPDP EVPDGLPPVA YNPWMDIRQR EDVQALNISV PYGPIPV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 34-290 of human IDS (NP_006114.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IDS

Target: IDS (Iduronate 2-Sulfatase (IDS))

Alternative Name: IDS

Background: This gene encodes a member of the sulfatase family of proteins. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.,IDS,MPS2,SIDS,Cell Biology & Developmental Biology,Ubiquitin,IDS

Molecular Weight: 34 kDa/38 kDa/61 kDa

Gene ID: 3423

UniProt: P22304

Pathways: Glycosaminoglycan Metabolic Process