Glycogen Synthase 1 antibody (AA 488-737)

Catalog No. ABIN3016178

This Rabbit Polyclonal antibody specifically detects Glycogen Synthase 1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for Glycogen Synthase 1 antibody (AA 488-737) (ABIN3016178)

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Glycogen Synthase 1 Antibody

Binding Specificity: AA 488-737

Sequence: LLPVDYEEFV RGCHLGVFPS YYEPWGYTPA ECTVMGIPSI STNLSGFGCF MEEHIADPSA YGIYILDRRF RSLDDSCSQL TSFLYSFCQQ SRRQRIIQRN RTERLSDLLD WKYLGRYYMS ARHMALSKAF PEHFTYEPNE ADAAQGYRYP RPASVPPSPS LSRHSSPHQS EDEEDPRNGP LEEDGERYDE DEEAAKDRRN IRAPEWPRRA SCTSSTSGSK RNSVDTATSS SLSTPSEPLS PTSSLGEERN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 488-737 of human Glycogen synthase 1 (Glycogen synthase 1 (GYS1)) (NP_002094.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Glycogen Synthase 1

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Alternative Name: GYS1

Background: The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,GYS1,GSY,GYS,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Carbohydrate metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Obesity,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,GYS1

Molecular Weight: 76 kDa/83 kDa

Gene ID: 2997

UniProt: P13807

Pathways: PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process