TNXB antibody (AA 444-673)

Catalog No. ABIN3016210

The Rabbit Polyclonal anti-TNXB antibody has been validated for WB. It is suitable to detect TNXB in samples from Human.

Quick Overview for TNXB antibody (AA 444-673) (ABIN3016210)

Target: TNXB (Tenascin XB (TNXB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNXB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNXB Antibody

Binding Specificity: AA 444-673

Sequence: TSFTTGGLRI PFPRDCGEEM QNGAGASRTS TIFLNGNRER PLNVFCDMET DGGGWLVFQR RMDGQTDFWR DWEDYAHGFG NISGEFWLGN EALHSLTQAG DYSMRVDLRA GDEAVFAQYD SFHVDSAAEY YRLHLEGYHG TAGDSMSYHS GSVFSARDRD PNSLLISCAV SYRGAWWYRN CHYANLNGLY GSTVDHQGVS WYHWKGFEFS VPFTEMKLRP RNFRSPAGGG

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 444-673 of human TNXB (NP_115859.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TNXB

Target: TNXB (Tenascin XB (TNXB))

Alternative Name: TNXB

Background: This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.,TNXB,EDS3,HXBL,TENX,TN-X,TNX,TNXB1,TNXB2,TNXBS,VUR8,XB,XBS,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,TNXB

Molecular Weight: 74 kDa/458 kDa

Gene ID: 7148

UniProt: P22105