FCGR3A antibody (AA 150-250)

Catalog No. ABIN3016244

The Rabbit Polyclonal anti-FCGR3A antibody (ABIN3016244) specifically detects FCGR3A in WB. The antibody is reactive with Human samples.

Quick Overview for FCGR3A antibody (AA 150-250) (ABIN3016244)

Target: FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCGR3A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FCGR3A Antibody

Binding Specificity: AA 150-250

Sequence: YFHHNSDFYI PKATLKDSGS YFCRGLFGSK NVSSETVNIT ITQGLAVSTI SSFFPPGYQV SFCLVMVLLF AVDTGLYFSV KTNIRSSTRD WKDHKFKWRK D

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human FCGR3A (NP_001121067.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FCGR3A

Target: FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))

Alternative Name: FCGR3A

Background: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CD16,CD16A,FCG3,FCGR3,FCGRIII,FCR-10,FCRIII,FCRIIIA,IGFR3,IMD20,FCGR3A,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,FCGR3A

Molecular Weight: 29 kDa

Gene ID: 2214

UniProt: P08637