ABCB8 antibody (AA 469-718)

Catalog No. ABIN3016382

The Rabbit Polyclonal anti-ABCB8 antibody has been validated for WB, IHC and IF. It is suitable to detect ABCB8 in samples from Human.

Quick Overview for ABCB8 antibody (AA 469-718) (ABIN3016382)

Target: ABCB8 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ABCB8 Antibody

Binding Specificity: AA 469-718

Sequence: GFEVLKDFTL TLPPGKIVAL VGQSGGGKTT VASLLERFYD PTAGVVMLDG RDLRTLDPSW LRGQVVGFIS QEPVLFGTTI MENIRFGKLE ASDEEVYTAA REANAHEFIT SFPEGYNTVV GERGTTLSGG QKQRLAIARA LIKQPTVLIL DEATSALDAE SERVVQEALD RASAGRTVLV IAHRLSTVRG AHCIVVMADG RVWEAGTHEE LLKKGGLYAE LIRRQALDAP RTAAPPPKKP EGPRSHQHKS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 469-718 of human ABCB8 (NP_009119.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ABCB8

Target: ABCB8 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))

Alternative Name: ABCB8

Background: This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.,ABCB8,EST328128,M-ABC1,MABC1,Signal Transduction,Endocrine & Metabolism,ABCB8

Molecular Weight: 59 kDa/68 kDa/75 kDa/78 kDa/79 kDa

Gene ID: 11194

UniProt: Q9NUT2