CFHR1 antibody (AA 151-330)

Catalog No. ABIN3016581

The Rabbit Polyclonal anti-CFHR1 antibody has been validated for WB. It is suitable to detect CFHR1 in samples from Human.

Quick Overview for CFHR1 antibody (AA 151-330) (ABIN3016581)

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFHR1 Antibody

Binding Specificity: AA 151-330

Sequence: PTVQNAHILS RQMSKYPSGE RVRYECRSPY EMFGDEEVMC LNGNWTEPPQ CKDSTGKCGP PPPIDNGDIT SFPLSVYAPA SSVEYQCQNL YQLEGNKRIT CRNGQWSEPP KCLHPCVISR EIMENYNIAL RWTAKQKLYL RTGESAEFVC KRGYRLSSRS HTLRTTCWDG KLEYPTCAKR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 151-330 of human CFHR1 (NP_002104.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CFHR1

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Alternative Name: CFHR1

Background: This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.,CFHR1,CFHL,CFHL1,CFHL1P,CFHR1P,FHR1,H36-1,H36-2,HFL1,HFL2,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood,Serum Proteins,CFHR1

Molecular Weight: 37 kDa

Gene ID: 3078

UniProt: Q03591