CFHR1 antibody
Quick Overview for CFHR1 antibody (ABIN7239977)
Target
See all CFHR1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of human CFHR1
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- CFHR1 (Complement Factor H-Related 1 (CFHR1))
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Alternative Name
- CFHR1
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Background
- This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
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Molecular Weight
- 38 kDa
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UniProt
- Q03591
Target
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