OPCML antibody (AA 246-345)

Catalog No. ABIN3016672

This Rabbit Polyclonal antibody specifically detects OPCML in WB. It exhibits reactivity toward Human.

Quick Overview for OPCML antibody (AA 246-345) (ABIN3016672)

Target: OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPCML antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OPCML Antibody

Binding Specificity: AA 246-345

Sequence: ASAVPMAEFQ WFKEETRLAT GLDGMRIENK GRMSTLTFFN VSEKDYGNYT CVATNKLGNT NASITLYGPG AVIDGVNSAS RALACLWLSG TLLAHFFIKF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 246-345 of human OPCML (NP_002536.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OPCML

Target: OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Alternative Name: OPCML

Background: This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,OPCML,IGLON1,OBCAM,OPCM,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cell Adhesion,Neuroscience,OPCML

Molecular Weight: 33 kDa/37 kDa/38 kDa

Gene ID: 4978

UniProt: Q14982