N-Cadherin antibody (AA 750-850)

Catalog No. ABIN3017243

This Rabbit Polyclonal antibody specifically detects N-Cadherin in WB and IP. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for N-Cadherin antibody (AA 750-850) (ABIN3017243)

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This N-Cadherin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-N-Cadherin Antibody

Binding Specificity: AA 750-850

Sequence: DKERQAKQLL IDPEDDVRDN ILKYDEEGGG EEDQDYDLSQ LQQPDTVEPD AIKPVGIRRM DERPIHAEPQ YPVRSAAPHP GDIGDFINEG LKAADNDPTA P

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 750-850 of human N-Cadherin (NP_001783.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IP,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-N-Cadherin antibody (ABIN3017243)

Shen, Sun, Sun, Li, Wu, Li, Chen, Liu, Cui, Zhou: "ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP." in: FEBS letters, Vol. 592, Issue 4, pp. 599-609, (2019) (PubMed).

Yan, Du, Li, Chen, Yan, Chen, Hu, Chang: "CO suppresses prostate cancer cell growth by directly targeting LKB1/AMPK/mTOR pathway in vitro and in vivo." in: Urologic oncology, Vol. 36, Issue 6, pp. 312.e1-312.e8, (2018) (PubMed).

Target Details for N-Cadherin

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Alternative Name: CDH2

Background: This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.,CD325,CDHN,CDw325,NCAD,N Cadherin,CDH2,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell Adhesion,Cadherins,Tight Junctions,Cytoskeleton,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CDH2

Molecular Weight: 97 kDa/99 kDa

Gene ID: 1000

UniProt: P19022

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane