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PAX5 antibody (AA 150-300)

This Rabbit Polyclonal antibody specifically detects PAX5 in WB. It exhibits reactivity toward Human.
Catalog No. ABIN3017307

Quick Overview for PAX5 antibody (AA 150-300) (ABIN3017307)

Target

See all PAX5 Antibodies
PAX5 (Paired Box 5 (PAX5))

Reactivity

  • 107
  • 54
  • 10
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 85
  • 17
  • 5
  • 1
Rabbit

Clonality

  • 74
  • 34
Polyclonal

Conjugate

  • 64
  • 7
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PAX5 antibody is un-conjugated

Application

  • 65
  • 46
  • 29
  • 16
  • 15
  • 14
  • 13
  • 10
  • 8
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 15
    • 9
    • 8
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-300

    Sequence

    PVPASSHSIV STGSVTQVSS VSTDSAGSSY SISGILGITS PSADTNKRKR DEGIQESPVP NGHSLPGRDF LRKQMRGDLF TQQQLEVLDR VFERQHYSDI FTTTEPIKPE QTTEYSAMAS LAGGLDDMKA NLASPTPADI GSSVPGPQSY P

    Cross-Reactivity

    Human

    Characteristics

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 150-300 of human PAX5 (NP_057953.1).

    Isotype

    IgG
  • Application Notes

    WB,1:1000 - 1:3000

    Restrictions

    For Research Use only
  • Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    PAX5 (Paired Box 5 (PAX5))

    Alternative Name

    PAX5

    Background

    This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms.,PAX5,ALL3,BSAP,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,PAX5

    Molecular Weight

    31 kDa/32 kDa/34 kDa/35 kDa/37 kDa/38 kDa/42 kDa

    Gene ID

    5079

    UniProt

    Q02548
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