beta Actin antibody

Catalog No. ABIN3020544

The Mouse Monoclonal anti-beta Actin antibody has been validated for WB, IF and IP. It is suitable to detect beta Actin in samples from Human. There are 67+ publications available.

Quick Overview for beta Actin antibody (ABIN3020544)

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This beta Actin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-beta Actin Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Loading control Antibodies

Purification: Affinity purification

Immunogen: Fusion protein of human beta-Actin

Isotype: IgG

Application Details

Application Notes: WB,1:10000 - 1:100000,IF,1:50- 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-beta Actin antibody (ABIN3020544)

Pan, Wang, Zhang, Zhang, Zhang, Wang, Xu, Zhang, Hu, Zhang, Du, Wang: "Hypoxia-induced microRNA-191 contributes to hepatic ischemia/reperfusion injury through the ZONAB/Cyclin D1 axis." in: Cell death and differentiation, Vol. 26, Issue 2, pp. 291-305, (2019) (PubMed).

Han, Cai, Gao, Meng, Gao, Wu, Duan, Wang, Dinislam, Lin, Kang, Jiang: "Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma." in: Cancer letters, Vol. 419, pp. 280-290, (2019) (PubMed).

Xu, Liu, Zha, Fan, Zhang, Li, Xiao: "A pathogen-derived effector modulates host glucose metabolism by arginine GlcNAcylation of HIF-1α protein." in: PLoS pathogens, Vol. 14, Issue 8, pp. e1007259, (2019) (PubMed).

Han, Gao, Gu, Hengstler, Zhang, Shahid, Ali, Han: "P21Waf1/Cip1 depletion promotes dexamethasone-induced apoptosis in osteoblastic MC3T3-E1 cells by inhibiting the Nrf2/HO-1 pathway." in: Archives of toxicology, Vol. 92, Issue 2, pp. 679-692, (2019) (PubMed).

Yang, Hu, Fan, Zhang, Zhong, Guo, Qin, Chen: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).

He, Yang, Niu, Zhong, Dan Gao, Zhang, Ma, Xiong, Zhou, Zhou, Xiang, Li, Shuai, Peng: "HMG-box transcription factor 1: a positive regulator of the G1/S transition through the Cyclin-CDK-CDKI molecular network in nasopharyngeal carcinoma." in: Cell death & disease, Vol. 9, Issue 2, pp. 100, (2018) (PubMed).

Guo, Zhao, Fei, Zhao, Zheng, Su, Wu, Li, Chang: "Dicer1 downregulation by multiple myeloma cells promotes the senescence and tumor-supporting capacity and decreases the differentiation potential of mesenchymal stem cells." in: Cell death & disease, Vol. 9, Issue 5, pp. 512, (2018) (PubMed).

Peng, Wang, Shu, Yang, Wang, Ouyang, Shen, Hou, Zhao, Wang, Zhang, Liu, Zhao: "Raddeanin a Suppresses Glioblastoma Growth by Inducing ROS Generation and Subsequent JNK Activation to Promote Cell Apoptosis." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 47, Issue 3, pp. 1108-1121, (2018) (PubMed).

Chen, Jiang, Li, Bai, Zhao, Zhang, Zhang: "Hydrogen protects against liver injury during CO2 pneumoperitoneum in rats." in: Oncotarget, Vol. 9, Issue 2, pp. 2631-2645, (2018) (PubMed).

Wang, Gu, Zhang, Zhang, Li, Yao, Yu, Zhang: "Angiotensin II Suppresses Rev-erbα Expression in THP-1 Macrophages via the Ang II Type 1 Receptor/Liver X Receptor α Pathway." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 46, Issue 1, pp. 303-313, (2018) (PubMed).

Zhao, Peng, Shu, Liu, Hou, Wang, Ye, Zhao, Wang, Zhong, Xue, Gao, Liu, Zhao: "Isogambogenic Acid Inhibits the Growth of Glioma Through Activation of the AMPK-mTOR Pathway." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 4, pp. 1381-1395, (2018) (PubMed).

Wang, Long, Chen, Fan, Wang, Li, Wu, Chen: "Inhibition of H3K4 demethylation induces autophagy in cancer cell lines." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1864, Issue 12, pp. 2428-2437, (2018) (PubMed).

Zhang, Wang, Zhang, Xiong, Zhang, Tang, Luo, Ma, Peng: "Vascular peroxide 1 promotes ox-LDL-induced programmed necrosis in endothelial cells through a mechanism involving β-catenin signaling." in: Atherosclerosis, Vol. 274, pp. 128-138, (2018) (PubMed).

Bai, Tang, Zou, Meng, Tu, Xia, Cheng, Zhang, Yang, Mu, Wang, Qin, Lv, Cao, Qin, Jiang, Chen: "m6A Demethylase FTO Regulates Dopaminergic Neurotransmission Deficits Caused by Arsenite." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 165, Issue 2, pp. 431-446, (2018) (PubMed).

Lei, Pan, Li, Zhou, Zhang, He, Peng, Li, Sidhu, Chen, Hua: "H19 regulates the proliferation of bovine male germline stem cells via IGF-1 signaling pathway." in: Journal of cellular physiology, Vol. 234, Issue 1, pp. 915-926, (2018) (PubMed).

Liu, Chen, Pei, Zhang, Zou, Xiao, Zhou, Chen, Wang: "Decreased H3K9ac level of StAR mediated testicular dysplasia induced by prenatal dexamethasone exposure in male offspring rats." in: Toxicology, Vol. 408, pp. 1-10, (2018) (PubMed).

Sheng, Yu, Chen, Wang, Lu: "Infection of grass carp reovirus induced the expressional suppression of pro-viral Fibulin-4 in host cells." in: Fish & shellfish immunology, Vol. 77, pp. 294-297, (2018) (PubMed).

He, Li, Wang, Hou, Li, Zhao: "Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction." in: International immunopharmacology, Vol. 50, pp. 208-215, (2018) (PubMed).

Chen, Zhou, Yang, Miao, Lu, Yang, Zhou, Kang, Chen, Zhou, Feng: "Neonatal Exposure to Low-Dose (1.2%) Sevoflurane Increases Rats' Hippocampal Neurogenesis and Synaptic Plasticity in Later Life." in: Neurotoxicity research, Vol. 34, Issue 2, pp. 188-197, (2018) (PubMed).

Lv, Sun, Mai, Jiang, Du: "STAT3 potentiates the ability of airway smooth muscle cells to promote angiogenesis by regulating VEGF signalling." in: Experimental physiology, Vol. 102, Issue 5, pp. 598-606, (2018) (PubMed).

Target Details for beta Actin

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Alternative Name: ACTB

Background: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.,ACTB,BRWS1,PS1TP5BP1,beta actin,actin,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Protein folding,Death Receptor Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,Immunology & Inflammation,ACTB

Molecular Weight: 41 kDa

Gene ID: 60

UniProt: P60709

Pathways: Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction