GCH1 antibody (Internal Region)

Catalog No. ABIN302137

This Goat Polyclonal antibody specifically detects GCH1 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for GCH1 antibody (Internal Region) (ABIN302137)

Target: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This GCH1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Grade: Verified

Product Details anti-GCH1 Antibody

Binding Specificity: Internal Region

Purpose: GCH1

Sequence: GKVHIGYLPN KQ

Specificity: This antibody is expected to recognize all four isoforms (NP_000152.1 , NP_001019195.1 , NP_001019241.1 , NP_001019242.1)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-GKVHIGYLPNKQ, from the internal region of the protein sequence according to NP_000152.1 , NP_001019195.1 , NP_001019241.1 , NP_001019242.1 .

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Brain (Cerebellum) and Small Intestine. Recommended concentration: 5 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for GCH1

Target: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Alternative Name: GCH1

Background: GCH1 , GTP cyclohydrolase 1 (dopa-responsive dystonia) , DYT5, GCH, GTP-CH-1, GTPCH1, GTP cyclohydrolase 1, guanosine 5'-triphosphate cyclohydrolase I

Gene ID: 2643, 14528, 29244

NCBI Accession: NP_000152, NP_001019195, NP_001019241, NP_001019242