Cullin 3 antibody (AA 569-768)

Catalog No. ABIN3021380

The Rabbit Polyclonal anti-Cullin 3 antibody has been validated for WB and IF. It is suitable to detect Cullin 3 in samples from Human.

Quick Overview for Cullin 3 antibody (AA 569-768) (ABIN3021380)

Target: Cullin 3 (CUL3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Cullin 3 Antibody

Binding Specificity: AA 569-768

Sequence: KEDGSEVGVG GAQVTGSNTR KHILQVSTFQ MTILMLFNNR EKYTFEEIQQ ETDIPERELV RALQSLACGK PTQRVLTKEP KSKEIENGHI FTVNDQFTSK LHRVKIQTVA AKQGESDPER KETRQKVDDD RKHEIEAAIV RIMKSRKKMQ HNVLVAEVTQ QLKARFLPSP VVIKKRIEGL IEREYLARTP EDRKVYTYVA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 569-768 of human Cullin 3 (NP_003581.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cullin 3

Target: Cullin 3 (CUL3)

Alternative Name: CUL3

Background: This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,CUL-3,PHA2E,CUL3,Cullin 3,cullin-3,Cancer,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,CUL3

Molecular Weight: 81 kDa/86 kDa/88 kDa

Gene ID: 8452

UniProt: Q13618

Pathways: M Phase