MAGED1 antibody (AA 635-834)

Catalog No. ABIN3021414

The Rabbit Polyclonal anti-MAGED1 antibody has been validated for WB and IHC. It is suitable to detect MAGED1 in samples from Human.

Quick Overview for MAGED1 antibody (AA 635-834) (ABIN3021414)

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGED1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MAGED1 Antibody

Binding Specificity: AA 635-834

Sequence: EAVLWEALRK MGLRPGVRHP LLGDLRKLLT YEFVKQKYLD YRRVPNSNPP EYEFLWGLRS YHETSKMKVL RFIAEVQKRD PRDWTAQFME AADEALDALD AAAAEAEARA EARTRMGIGD EAVSGPWSWD DIEFELLTWD EEGDFGDPWS RIPFTFWARY HQNARSRFPQ TFAGPIIGPG GTASANFAAN FGAIGFFWVE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 635-834 of human MAGED1 (NP_001005333.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Alternative Name: MAGED1

Background: This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.,MAGED1,DLXIN-1,NRAGE,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,MAGED1

Molecular Weight: 86 kDa/91 kDa

Gene ID: 9500

UniProt: Q9Y5V3

Pathways: Neurotrophin Signaling Pathway