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IL-18 antibody (AA 37-193)
IL18
Reactivity: Human
WB, IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL-18 Antibody
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Target
See all IL-18 (IL18) Antibodies
IL-18 (IL18)
(Interleukin 18 (IL18))
Binding Specificity
All epitopes for IL-18 antibodies
AA 37-193
Reactivity
All reactivities for IL-18 antibodies
Human
Host
All hosts for IL-18 antibodies
Rabbit
Clonality
All clonalities for IL-18 antibodies
Polyclonal
Conjugate
All conjugates for IL-18 antibodies
This IL-18 antibody is un-conjugated
Application
All applications for IL-18 antibodies
Western Blotting (WB), Immunoprecipitation (IP)
Sequence
YFGKLESKLS VIRNLNDQVL FIDQGNRPLF EDMTDSDCRD NAPRTIFIIS MYKDSQPRGM AVTISVKCEK ISTLSCENKI ISFKEMNPPD NIKDTKSDII FFQRSVPGHD NKMQFESSSY EGYFLACEKE RDLFKLILKK EDELGDRSIM FTVQNED
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 37-193 of human IL18 (NP_001553.1).
Isotype
IgG
Top Product
Discover our top product IL18 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IP,1:50 - 1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-IL-18 antibody (ABIN3021465)
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Wu, Zhang, Qi, Zhang, Li, Li, Lin, Bai, Liu, Chen, Yang, Xu, Zhang, Yang : "Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis. " in: Cell death & disease , Vol. 9 , Issue 2 , pp. 171 , (2018 ) (PubMed ).
Du, Qiao, Chen, Chen, Liu, Lin, Wang, Xie : "Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes. " in: Frontiers in molecular neuroscience , Vol. 10 , pp. 409 , (2017 ) (PubMed ).
Target Details for IL-18
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Target
IL-18 (IL18)
(Interleukin 18 (IL18))
Alternative Name
IL18 (IL18 Products )
Background
The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,IL18,IGIF,IL-18,IL-1g,IL1F4,Cancer,Tumor immunology,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Endocrine & Metabolism,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Angiogenesis,Angiogenic growth factors,IL18
Molecular Weight
21 kDa/22 kDa
Gene ID
3606
UniProt
Q14116
Pathways
Cellular Response to Molecule of Bacterial Origin , Activated T Cell Proliferation , Cancer Immune Checkpoints , Inflammasome
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