PFN1 antibody (AA 1-140)

Catalog No. ABIN3021599

The Rabbit Polyclonal anti-PFN1 antibody has been validated for WB. It is suitable to detect PFN1 in samples from Human.

Quick Overview for PFN1 antibody (AA 1-140) (ABIN3021599)

Target: PFN1 (Profilin 1 (PFN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PFN1 Antibody

Binding Specificity: AA 1-140

Sequence: MAGWNAYIDN LMADGTCQDA AIVGYKDSPS VWAAVPGKTF VNITPAEVGV LVGKDRSSFY VNGLTLGGQK CSVIRDSLLQ DGEFSMDLRT KSTGGAPTFN VTVTKTDKTL VLLMGKEGVH GGLINKKCYE MASHLRRSQY

Cross-Reactivity: Human, Monkey, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human Profilin1 (NP_005013.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PFN1

Target: PFN1 (Profilin 1 (PFN1))

Alternative Name: PFN1

Background: This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.,PFN1,ALS18,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Cytoskeleton,Microfilaments,Actins,Neuroscience,Cell Type Marker,Neuron marker,Synapse marker,PFN1

Molecular Weight: 15 kDa

Gene ID: 5216

UniProt: P07737

Pathways: Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location