SMPD2 antibody (AA 150-250)

Catalog No. ABIN3021605

This Rabbit Polyclonal antibody specifically detects SMPD2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for SMPD2 antibody (AA 150-250) (ABIN3021605)

Target: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMPD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SMPD2 Antibody

Binding Specificity: AA 150-250

Sequence: AHRVAQAWEL AQFIHHTSKK ADVVLLCGDL NMHPEDLGCC LLKEWTGLHD AYLETRDFKG SEEGNTMVPK NCYVSQQELK PFPFGVRIDY VLYKAVSGFY I

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SMPD2 (NP_003071.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMPD2

Target: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Alternative Name: SMPD2

Background: This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase.,SMPD2,ISC1,NSMASE,NSMASE1,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Oligodendrocyte marker,SMPD2

Molecular Weight: 47 kDa

Gene ID: 6610

UniProt: O60906

Pathways: Neurotrophin Signaling Pathway