EpCAM antibody (AA 40-260)

Catalog No. ABIN3021638

This Rabbit Polyclonal antibody specifically detects EpCAM in WB and IF. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for EpCAM antibody (AA 40-260) (ABIN3021638)

Target: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EpCAM antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-EpCAM Antibody

Binding Specificity: AA 40-260

Sequence: VNNNRQCQCT SVGAQNTVIC SKLAAKCLVM KAEMNGSKLG RRAKPEGALQ NNDGLYDPDC DESGLFKAKQ CNGTSMCWCV NTAGVRRTDK DTEITCSERV RTYWIIIELK HKAREKPYDS KSLRTALQKE ITTRYQLDPK FITSILYENN VITIDLVQNS SQKTQNDVDI ADVAYYFEKD VKGESLFHSK KMDLTVNGEQ LDLDPGQTLI YYVDEKAPEF S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-260 of human EpCAM (NP_002345.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-EpCAM antibody (ABIN3021638)

Zhou, Wang, Liu, Xue, Lin, Meng, Liang, Zhao, Liu, Qian: "MTA1-upregulated EpCAM is associated with metastatic behaviors and poor prognosis in lung cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 157, (2016) (PubMed).

Target Details for EpCAM

Target: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Alternative Name: EPCAM

Background: This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.,EPCAM,DIAR5,EGP-2,EGP314,EGP40,ESA,HNPCC8,KS1/4,KSA,M4S1,MIC18,MK-1,TACSTD1,TROP1,Immunology & Inflammation,CD markers,EPCAM

Molecular Weight: 34 kDa

Gene ID: 4072

UniProt: P16422