Caspase 7 antibody (AA 24-303)

Catalog No. ABIN3022072

This anti-Caspase 7 antibody is a Rabbit Polyclonal antibody detecting Caspase 7 in WB and IHC. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Caspase 7 antibody (AA 24-303) (ABIN3022072)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Caspase 7 Antibody

Binding Specificity: AA 24-303

Sequence: AKPDRSSFVP SLFSKKKKNV TMRSIKTTRD RVPTYQYNMN FEKLGKCIII NNKNFDKVTG MGVRNGTDKD AEALFKCFRS LGFDVIVYND CSCAKMQDLL KKASEEDHTN AACFACILLS HGEENVIYGK DGVTPIKDLT AHFRGDRCKT LLEKPKLFFI QACRGTELDD GIQADSGPIN DTDANPRYKI PVEADFLFAY STVPGYYSWR SPGRGSWFVQ ALCSILEEHG KDLEIMQILT RVNDRVARHF ESQSDDPHFH EKKQIPCVVS MLTKELYFSQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-303 of human Caspase-7 (NP_001218.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Caspase 7 antibody (ABIN3022072)

Wu, Xiong, Li, Yang, Ge et al.: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).

Target Details for Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Alternative Name: Casp7

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,CASP7,CASP-7,CMH-1,ICE-LAP3,LICE2,MCH3,caspase-7,Casp7,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Casp7

Molecular Weight: 28 kDa/31 kDa/34 kDa/37 kDa

Gene ID: 840

UniProt: P55210

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity