SERPINC1
Reactivity: Human, Mouse
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
SERPINC1
(Serpin Family C Member 1 (SERPINC1))
Alternative Name
SERPINC1
Background
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.,SERPINC1,AT3,AT3D,ATIII,THPH7,Stem Cells,Cardiovascular,Blood,Coagulation,Serum Proteins,SERPINC1