IL23R antibody (AA 405-629)

Catalog No. ABIN3022246

The Rabbit Polyclonal anti-IL23R antibody has been validated for WB, IHC and IF. It is suitable to detect IL23R in samples from Human.

Quick Overview for IL23R antibody (AA 405-629) (ABIN3022246)

Target: IL23R (Interleukin 23 Receptor (IL23R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL23R antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IL23R Antibody

Binding Specificity: AA 405-629

Sequence: NSNVVKMLQE NSELMNNNSS EQVLYVDPMI TEIKEIFIPE HKPTDYKKEN TGPLETRDYP QNSLFDNTTV VYIPDLNTGY KPQISNFLPE GSHLSNNNEI TSLTLKPPVD SLDSGNNPRL QKHPNFAFSV SSVNSLSNTI FLGELSLILN QGECSSPDIQ NSVEEETTML LENDSPSETI PEQTLLPDEF VSCLGIVNEE LPSINTYFPQ NILESHFNRI SLLEK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 405-629 of human IL23R (NP_653302.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL23R

Target: IL23R (Interleukin 23 Receptor (IL23R))

Alternative Name: IL23R

Background: The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.,IL23R,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL23R

Molecular Weight: 20 kDa/25 kDa/30 kDa/40 kDa/42 kDa/71 kDa

Gene ID: 149233

UniProt: Q5VWK5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation