L-Selectin antibody (AA 1-100)
Quick Overview for L-Selectin antibody (AA 1-100) (ABIN3022264)
Target
See all L-Selectin (SELL) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-100
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Sequence
- MGCRRTREGP SKAMIFPWKC QSTQRDLWNI FKLWGWTMLC CDFLAHHGTD CWTYHYSEKP MNWQRARRFC RDNYTDLVAI QNKAEIEYLE KTLPFSRSYY
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SELL (NP_000646.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid freeze / thaw cycles
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- L-Selectin (SELL) (Selectin L (SELL))
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Alternative Name
- SELL
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Background
- This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.,SELL,CD62L,LAM1,LECAM1,LEU8,LNHR,LSEL,LYAM1,PLNHR,TQ1,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Blood,SELL
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Molecular Weight
- 42 kDa/43 kDa
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Gene ID
- 6402
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UniProt
- P14151
Target
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