PTH1R antibody (AA 464-593)

Catalog No. ABIN3022478

The Rabbit Polyclonal anti-PTH1R antibody has been validated for WB and IHC. It is suitable to detect PTH1R in samples from Human.

Quick Overview for PTH1R antibody (AA 464-593) (ABIN3022478)

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTH1R antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PTH1R Antibody

Binding Specificity: AA 464-593

Sequence: GEVQAEIKKS WSRWTLALDF KRKARSGSSS YSYGPMVSHT SVTNVGPRVG LGLPLSPRLL PTATTNGHPQ LPGHAKPGTP ALETLETTPP AMAAPKDDGF LNGSCSGLDE EASGPERPPA LLQEEWETVM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 464-593 of human PTH1R (NP_000307.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTH1R

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Alternative Name: PTH1R

Background: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.,PTH1R,PFE,PTHR,PTHR1,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,PTH1R

Molecular Weight: 66 kDa

Gene ID: 5745

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process