CD33 antibody (AA 49-259)

Catalog No. ABIN3022816

This Rabbit Polyclonal antibody specifically detects CD33 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for CD33 antibody (AA 49-259) (ABIN3022816)

Target: CD33

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD33 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CD33 Antibody

Binding Specificity: AA 49-259

Sequence: YYDKNSPVHG YWFREGAIIS RDSPVATNKL DQEVQEETQG RFRLLGDPSR NNCSLSIVDA RRRDNGSYFF RMERGSTKYS YKSPQLSVHV TDLTHRPKIL IPGTLEPGHS KNLTCSVSWA CEQGTPPIFS WLSAAPTSLG PRTTHSSVLI ITPRPQDHGT NLTCQVKFAG AGVTTERTIQ LNVTYVPQNP TTGIFPGDGS GKQETRAGVV H

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 49-259 of human SIGLEC3/CD33 (NP_001763.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD33

Target: CD33

Alternative Name: CD33

Background: Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This Single-pass type I membrane protein contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD33/Siglec-3 induces apoptosis in acute myeloid leukemia (in vitro). CD33/Siglec-3 can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when CD33 is expressed in a plasma membrane.,CD33,SIGLEC-3,SIGLEC3,p67,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CD33

Molecular Weight: 25 kDa/33 kDa/39 kDa

Gene ID: 945

UniProt: P20138