CD51 antibody (C-Term)
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- Target See all CD51 (ITGAV) Antibodies
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD51 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Sequence
- LKSSASFNVI EFPYKNLPIE DITNSTLVTT NVTWGIQPAP MPVPVWVIIL AVLAGLLLLA VLVFVMYRMG FFKRVRPPQE EQEREQLQPH ENGEGNSET
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 950 to the C-terminus of human Integrin alpha V (ITGAV/CD51) (NP_002201.1).
- Isotype
- IgG
- Top Product
- Discover our top product ITGAV Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Alternative Name
- ITGAV (ITGAV Products)
- Background
- The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.,CD51,MSK8,VNRA,VTNR,Integrin alpha V,ITGAV,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Immunology & Inflammation,CD markers,ITGAV
- Molecular Weight
- 111 kDa/112 kDa/116 kDa
- Gene ID
- 3685
- UniProt
- P06756
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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