CD31 antibody (AA 130-230)

Catalog No. ABIN3022924

This anti-CD31 antibody is a Rabbit Polyclonal antibody detecting CD31 in WB, IHC and IF. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for CD31 antibody (AA 130-230) (ABIN3022924)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD31 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CD31 Antibody

Binding Specificity: AA 130-230

Sequence: VPSPRVTLDK KEAIQGGIVR VNCSVPEEKA PIHFTIEKLE LNEKMVKLKR EKNSRDQNFV ILEFPVEEQD RVLSFRCQAR IISGIHMQTS ESTKSELVTV T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 130-230 of human CD31/PECAM1 (NP_000433.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-CD31 antibody (ABIN3022924)

Ruan, Ren, Zhang, Zhu, Xu, Wang: "Cardioprotective Effects of QiShenYiQi Dripping Pills on Transverse Aortic Constriction-Induced Heart Failure in Mice." in: Frontiers in physiology, Vol. 9, pp. 324, (2018) (PubMed).

Li, Wu, Yuan, Sun, Lin, Huang, Bin, Liao, Liao: "Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis." in: Cancer letters, Vol. 395, pp. 31-44, (2017) (PubMed).

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: PECAM1

Background: The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.,CD31,CD31/EndoCAM,PECA1,PECAM-1,endoCAM,PECAM1,Cancer,Tumor immunology,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,Mesenchymal Stem Cells,Cardiovascular,Angiogenesis,Blood,PECAM1

Molecular Weight: 79 kDa/80 kDa/81 kDa/82 kDa

Gene ID: 5175

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization