KLF5
Reactivity: Human, Mouse, Rat, Cow, Pig, Dog
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB,1:200 - 1:1000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
KLF5
(Kruppel-Like Factor 5 (Intestinal) (KLF5))
Alternative Name
KLF5
Background
This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants.,KLF5,BTEB2,CKLF,IKLF,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Angiogenesis,Heart,Hypertrophy,KLF5