Histone H2A antibody (pSer139)
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- Target See all Histone H2A Antibodies
- Histone H2A
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Binding Specificity
- pSer139
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Histone H2A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TQASQ
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Phosphorylated Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthetic phosphorylated peptide around S139 of human Histone H2AX (NP_002096.1).
- Isotype
- IgG
- Top Product
- Discover our top product Histone H2A Primary Antibody
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- Application Notes
- WB,1:500 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
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RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
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- Target
- Histone H2A
- Abstract
- Histone H2A Products
- Background
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.,H2A.X,H2A/X,H2AX,Histone H2AX,H2AFX,histone H2AX,gamma H2A.X,γH2AX,Epigenetics & Nuclear Signaling,Histones,DNA Damage & Repair,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Phosphorylation,Histone H2A
- Molecular Weight
- 15 kDa
- Gene ID
- 3014
- UniProt
- P16104
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