Recombinant PD-1 antibody

Catalog No. ABIN3023753

This Rabbit Monoclonal antibody specifically detects PD-1 in IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant PD-1 antibody (ABIN3023753)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PD-1 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RMPD1-1

Product Details anti-PD-1 Antibody

Purification: Protein A affinity chromatography

Immunogen: Full length recombinant human protein was used as the immunogen for the rabbit monoclonal PD-1 antibody.

Isotype: IgG kappa

Application Details

Application Notes: Titering of the PD-1 antibody may be required for optimal performance.

1. FFPE testing is enhanced by boiling tissue in 10  mM Tris with 1  mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 min\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1),Immunofluorescence: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the PD-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: PD-1

Background: Programmed cell death protein 1 is an inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors. [UniProt]

Pathways: Cancer Immune Checkpoints