TRIL
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.\. Western blot: 2-5 μg/mL
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
TRIL
(TLR4 Interactor with Leucine-Rich Repeats (TRIL))
Alternative Name
TRIL
Background
TRIL or TLR4 interactor with leucine rich repeats, is a protein encoded by the human KIAA0644 gene. TRIL protein sequence is highly conserved across species. It is expressed in a number of tissues with highest expression in brain, ovary, small intestine and spleen. TRIL is an accessory molecule that interacts with TLR3 and endosomal TLR4, enhancing their interaction with their ligands, poly(I:C) and LPS, and increasing the production of type I interferons in the innate immune response.