CCR4 antibody (2nd Extracellular Domain)

Catalog No. ABIN302479

This Rabbit Polyclonal antibody specifically detects CCR4 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for CCR4 antibody (2nd Extracellular Domain) (ABIN302479)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CCR4 Antibody

Binding Specificity: 2nd Extracellular Domain

Specificity: This antibody detects C-C Chemokine Receptor 4 (CCR4) at 2nd extracellular domain.

Purification: Immunoaffinity Chromatography

Immunogen: CCR4 antibody was raised against synthetic 18 amino acid peptide from 2nd extracellular domain of Human CCR4.

Application Details

Application Notes: Immunohistochemistry on paraffin sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CD194 / CCR4

Background: CCR4, a Chemokine Receptor, mediates inflammatory responses and HIV-1 infections. It binds beta-family chemokines (CC motif) such as TARC (thymus and activation-regulated chemokine) and MDC (macrophage-derived chemokine).Synonyms: C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR-4, CMKBR4, K5-5

Gene ID: 1233

NCBI Accession: NP_005499

UniProt: P51679