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Rabies Virus antibody

The Mouse Monoclonal anti-Rabies Virus antibody has been validated for ELISA, IF and ICC. It is suitable to detect Rabies Virus in samples from Rabies Virus.
Catalog No. ABIN3025497

Quick Overview for Rabies Virus antibody (ABIN3025497)

Target

Rabies Virus (RABV)

Reactivity

  • 26
  • 10
Rabies Virus

Host

  • 36
Mouse

Clonality

  • 35
  • 1
Monoclonal

Conjugate

  • 15
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Rabies Virus antibody is un-conjugated

Application

  • 24
  • 19
  • 12
  • 10
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone

Rab-50
  • Characteristics

    Reacts with viral glycoprotein of rabies virus strains SAD-Vnukovo and Pitman-Moore. This mAb is useful in detecting rabies virus by ELISA and Western. It is capable of neutralizing rabies virus. Rabies virus (Neurotropic virus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumb like glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Lipid solvents destroy virus infectivity. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.

    Purification

    Protein G affinity chromatography

    Immunogen

    Purified virions of SAD-Vnukovo strain followed by Pitman-Moore strain was used as the immunogen for the Rabies Virus antibody.

    Isotype

    IgG2b kappa
  • Application Notes

    Optimal dilution of the Rabies Virus antibody should be determined by the researcher.\. ELISA (order Ab without BSA),Immunocytochemistry (Acetone-fixed frozen): 0.5-1 μg/mL for 30 min,Immunofluorescence: 0.5-1 μg/mL

    Restrictions

    For Research Use only
  • Concentration

    0.2 mg/mL

    Buffer

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store the Rabies Virus antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target

    Rabies Virus (RABV)

    Alternative Name

    Rabies Virus

    Target Type

    Virus

    Background

    Reacts with viral glycoprotein of rabies virus strains SAD-Vnukovo and Pitman-Moore. This mAb is useful in detecting rabies virus by ELISA and Western. It is capable of neutralizing rabies virus. Rabies virus (Neurotropic virus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumb like glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Lipid solvents destroy virus infectivity. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.
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