PAX7 antibody (AA 301-505)

Catalog No. ABIN3026249

This Mouse Monoclonal antibody specifically detects PAX7 in WB, FACS and IF. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio) and Chicken.

Quick Overview for PAX7 antibody (AA 301-505) (ABIN3026249)

Target: PAX7 (Paired Box 7 (PAX7))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PAX7-497

Product Details anti-PAX7 Antibody

Binding Specificity: AA 301-505

Purification: Protein G affinity chromatography

Immunogen: Recombinant human PAX7 protein corresponding to amino acids 301-505 was used as the immunogen for this antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the PAX7 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for PAX7

Target: PAX7 (Paired Box 7 (PAX7))

Alternative Name: PAX7

Background: The PAX gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the PAX family of proteins have been linked to disease and cancer in humans. PAX7 is a protein specifically expressed in cultured satellite cell- derived myoblasts. In situ hybridization reveals that PAX7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding PAX7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Gene ID: 5081