COX2 antibody (AA 589-604)

Catalog No. ABIN3028607

The Rabbit Polyclonal anti-COX2 antibody is suitable to detect COX2 in samples from Human. It has been validated for WB, IHC (p) and IHC (fro).

Quick Overview for COX2 antibody (AA 589-604) (ABIN3028607)

Target: COX2 (Cytochrome C Oxidase Subunit II (COX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-COX2 Antibody

Binding Specificity: AA 589-604

Purification: Antigen affinity

Immunogen: Amino acids 589-604 (DDINPTVLLKERSTEL-human) were used as the immunogen for this COX2 antibody.

Isotype: IgG

Application Details

Application Notes: Titration of the COX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: The lyophilized COX2 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for COX2

Target: COX2 (Cytochrome C Oxidase Subunit II (COX2))

Alternative Name: COX2

Background: Cyclooxygenase (COX) is the key enzyme in conversion of arachidonic acid to PGs. The COX2 gene encodes an inducible prostaglandin synthase enzyme that is overexpressed in adenocarcinomas and other tumors. Deletion of the murine gene in Min mice reduced the incidence of intestinal tumors, suggesting that it is required for tumorigenesis.

UniProt: P35354

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation