SDC3 antibody (N-Term)

Catalog No. ABIN3029080

This Rabbit Polyclonal antibody specifically detects SDC3 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SDC3 antibody (N-Term) (ABIN3029080)

Target: SDC3 (Syndecan 3 (SDC3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SDC3 Antibody

Binding Specificity: N-Term

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of mouse Syndecan 3 (AQRWRNENFERPVDLE) was used as the immunogen for this Syndecan 3 antibody (100% rat homology).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Syndecan 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Syndecan 3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for SDC3

Target: SDC3 (Syndecan 3 (SDC3))

Alternative Name: Syndecan 3

Background: Syndecan-3, also called SYND3, is a protein that in humans is encoded by the SDC3 gene. This gene was assigned to human chromosome 1p35.2. This gene can function as in trans HIV receptors via binding of HIV-1 gp120 to the syndecan heparin sulfate chains. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, and possibly by transferring signals from the cell surface in a sugar-dependent mechanism. In wildtype mice, SDC3 was expressed in hypothalamic regions that control energy balance. It was proposed that oscillation of hypothalamic SDC3 levels physiologically modulates feeding behavior.

UniProt: Q64519

Pathways: Glycosaminoglycan Metabolic Process