ABI2 antibody (N-Term)

Catalog No. ABIN3029825

The Rabbit Polyclonal anti-ABI2 antibody has been validated for WB. It is suitable to detect ABI2 in samples from Human, Mouse and Rat.

Quick Overview for ABI2 antibody (N-Term) (ABIN3029825)

Target: ABI2 (Abl-Interactor 2 (ABI2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABI2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ABI2 Antibody

Binding Specificity: N-Term

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human ABL Interactor 2 (RFKVSTQNMKMGGLPR) was used as the immunogen for this ABI2 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the ABI2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the ABI2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ABI2

Target: ABI2 (Abl-Interactor 2 (ABI2))

Alternative Name: ABI2

Background: ABL Interactor 2 is a protein that in humans is encoded by the ABI2 gene. By analysis of a YAC and a BAC, Machado et al.(2000) mapped the gene to 2q31-q33. ABI2 possesses a basic N terminus with homology to a homeodomain protein, a central serine-rich region, three PEST sequences, which are implicated in susceptibility to protein degradation, several proline-rich stretches, and an acidic C terminus with multiple phosphorylation sites and an SH3 domain. Dai and Pendergast(1995) suggested that the ABI proteins may function to coordinate the cytoplasmic and nuclear functions of the ABL1 tyrosine kinase.

UniProt: Q9NYB9