Caspase 7 antibody (AA 237-255)

Catalog No. ABIN3030315

This anti-Caspase 7 antibody is a Rabbit Polyclonal antibody detecting Caspase 7 in WB and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for Caspase 7 antibody (AA 237-255) (ABIN3030315)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Caspase 7 Antibody

Binding Specificity: AA 237-255

Purification: Antigen affinity

Immunogen: Amino acids 237-255 (RGSWFVQALCSILEEHGKD-human) were used as the immunogen for this Caspase-7 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Caspase-7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Caspase-7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Alternative Name: Caspase-7

Background: Caspase-7 is a human protein encoded by the CASP7 gene. Orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the cysteine aspartate protease family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of the protein regulates microglia activation through a protein kinase C-delta (PRKCD)-dependent pathway.

UniProt: P55210

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity