LASP1 antibody (C-Term)

Catalog No. ABIN3031620

Product Details anti-LASP1 Antibody

Target: LASP1 (LIM and SH3 Protein 1 (LASP1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LASP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human LASP1 (YRRPLEQQQPHHIPTSA) was used as the immunogen for this LASP1 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the LASP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the LASP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for LASP1

Target: LASP1 (LIM and SH3 Protein 1 (LASP1))

Alternative Name: LASP1 (LASP1 Products)

Synonyms: lasp1 antibody, MGC53336 antibody, LASP1 antibody, MGC89667 antibody, Lasp-1 antibody, MLN50 antibody, AA408629 antibody, Def-4 antibody, SH3P6 antibody, Tg(Col1a1-lacZ)1Ngma antibody, fb92f05 antibody, wu:fb92f05 antibody, zgc:77542 antibody, lasp-1 antibody, mln50 antibody, LIM and SH3 protein 1 antibody, LIM and SH3 protein 1 L homeolog antibody, lasp1 antibody, lasp1.L antibody, LASP1 antibody, Lasp1 antibody

Background: LIM and SH3 domain protein 1 is a protein that in humans is encoded by the LASP1 gene. This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization. LASP1 has been shown to interact with Zyxin. Northern blot analysis revealed that LASP1 mRNA was expressed at a basal level in all normal tissues examined and overexpressed in 8 % of primary breast cancers. In most of these cancers, LASP1 and ERBB2 were simultaneously overexpressed.

UniProt: Q14847