MCM5 antibody (C-Term)

Catalog No. ABIN3031806

This anti-MCM5 antibody is a Rabbit Polyclonal antibody detecting MCM5 in WB and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for MCM5 antibody (C-Term) (ABIN3031806)

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MCM5 Antibody

Binding Specificity: C-Term

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human MCM5 (EIQHRMQRKVLYRLK) was used as the immunogen for this MCM5 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the MCM5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the MCM5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for MCM5

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Alternative Name: MCM5

Background: Minichromosome maintenance, S. cerevisiae, homolog of, 5, also known as CDC46, is a protein that in humans is encoded by the MCM5 gene. The protein is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. And it is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The MCM5 gene contains 16 exons and the encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

UniProt: P33992

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA