Myeloperoxidase antibody (AA 406-745)
Quick Overview for Myeloperoxidase antibody (AA 406-745) (ABIN3031897)
Target
See all Myeloperoxidase (MPO) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 406-745
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Purification
- Antigen affinity
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Immunogen
- Human partial recombinant protein (AA 406-745) was used as the immunogen for this MPO antibody.
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Isotype
- IgG
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the MPO antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- -20 °C
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Storage Comment
- After reconstitution, the MPO antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Myeloperoxidase (MPO)
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Alternative Name
- MPO Myeloperoxidase
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Background
- Myeloperoxidase is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. MPO is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. Located in the nucleus as well as in the cytoplasm, intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function.
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Gene ID
- 4353
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Pathways
- Chromatin Binding
Target
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