Western Blot. Immunohistochemistry on Paraffin Sections (5 μg/mL). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
P53AIP1 antibody, tumor protein p53 regulated apoptosis inducing protein 1 antibody, TP53AIP1 antibody
Background
P53AIP1 is located in mitochondria and its overexpression results in growth suppression and apoptosis. The induction of p53AIP1 transcription in response to DNA damage is dependent on phosphorylation of p53 at Ser-46. The p53AIP1 gene has 3 major transcripts, designated alpha, beta and gamma.Synonyms: p53-regulated apoptosis-inducing protein 1, p53AIP1