CCL17 antibody (AA 34-103)

Catalog No. ABIN3042354

This anti-CCL17 antibody is a Rabbit Polyclonal antibody detecting CCL17 in WB and ELISA. Suitable for Mouse.

Quick Overview for CCL17 antibody (AA 34-103) (ABIN3042354)

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCL17 Antibody

Binding Specificity: AA 34-103

Purpose: Anti-TARC/CCL17 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-TARC/CCL17 Antibody Picoband® (ABIN3042354). Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse TARC recombinant protein (Position: A34-P103). Mouse TARC shares 71% amino acid (aa) sequence identity with human TARC.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Mouse, -
ELISA, 0.1-0.5 μg/mL, -
1. Imai T, Yoshida T, Baba M, Nishimura M, Kakizaki M, Yoshie O (1996). "Molecular cloning of a novel T cell-ed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector". J. Biol. Chem. 271 (35): 21514-21. 2. Imai T, Baba M, Nishimura M, Kakizaki M, Takagi S, Yoshie O (1997). "The T cell-ed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4". J. Biol. Chem. 272 (23): 15036-42. 3. Nomiyama H, Imai T, Kusuda J, Miura R, Callen DF, Yoshie O (1997). "Assignment of the human CC chemokine gene TARC (SCYA17) to chromosome 16q13". Genomics 40 (1): 211-3. 4. Nomiyama H, Imai T, Kusuda J, Miura R, Callen DF, Yoshie O (1998). "Human chemokines fractalkine (SCYD1), MDC (SCYA22) and TARC (SCYA17) are clustered on chromosome 16q13". Cytogenet. Cell Genet. 81 (1): 10-1.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CCL17

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Alternative Name: CCL17

Background:

Synonyms: C-C motif chemokine ,Ccl17 ,ABCD-2 , TARC ,mCG_12286 ,

Tissue Specificity: Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.

Background: Chemokine (C-C motif) ligand 17 (CCL17) is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). CCL17 is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. This chemokine specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. The gene for CCL17 is located on chromosome 16, in humans, along with other chemokines called CCL22 and CX3CL1. The standard used in this kit is recombinant human CCL17, consisting of 71 amino acids with the molecular weight of 8Kda.

Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

Molecular Weight: 34 kDa

Gene ID: 20295