CCL17 antibody (C-Term)

Catalog No. ABIN1881150

Product Details anti-CCL17 Antibody

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Binding Specificity: AA 65-94, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL17 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCL17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the C-terminal region of human CCL17.

Clone: RB40883

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CCL17 antibody (ABIN1881150)

Dallos, Heiland, Strehl, Karonitsch, Gross, Moosig, Holl-Ulrich, Distler, Manger, Schett, Zwerina: "CCL17/thymus and activation-related chemokine in Churg-Strauss syndrome." in: Arthritis and rheumatism, Vol. 62, Issue 11, pp. 3496-503, (2010) (PubMed).

Maruyama, Kono, Izawa, Mizukami, Kawaguchi, Mimura, Watanabe, Fujii: "CCL17 and CCL22 chemokines within tumor microenvironment are related to infiltration of regulatory T cells in esophageal squamous cell carcinoma." in: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E, Vol. 23, Issue 5, pp. 422-9, (2010) (PubMed).

Schuurhof, Bont, Siezen, Hodemaekers, van Houwelingen, Kimman, Hoebee, Kimpen, Janssen: "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls." in: Pediatric pulmonology, Vol. 45, Issue 6, pp. 608-13, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Target Details for CCL17

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Alternative Name: CCL17 (CCL17 Products)

Synonyms: A-152E5.3 antibody, ABCD-2 antibody, SCYA17 antibody, TARC antibody, CCL17 antibody, Abcd-2 antibody, Scya17 antibody, Scya17l antibody, Tarc antibody, abcd2 antibody, C-C motif chemokine ligand 17 antibody, chemokine (C-C motif) ligand 17 antibody, ATP-binding cassette sub-family D member 2 antibody, CCL17 antibody, Ccl17 antibody, LOC100537809 antibody

Background: This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

Molecular Weight: 10507

NCBI Accession: NP_002978

UniProt: Q92583