EPB41L1 antibody (AA 691-881)

Catalog No. ABIN3042373

This Rabbit Polyclonal antibody specifically detects EPB41L1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for EPB41L1 antibody (AA 691-881) (ABIN3042373)

Target: EPB41L1 (erythrocyte Membrane Protein Band 4.1-Like 1 (EPB41L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPB41L1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPB41L1 Antibody

Binding Specificity: AA 691-881

Purpose: Anti-EPB41L1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-EPB41L1 Antibody (ABIN3042373). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EPB41L1 recombinant protein (Position: Q691-S881). Human EPB41L1 shares 91% amino acid (aa) sequence identity with both mouse and rat EPB41L1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for EPB41L1

Target: EPB41L1 (erythrocyte Membrane Protein Band 4.1-Like 1 (EPB41L1))

Alternative Name: EPB41L1

Background:

Synonyms: Band 4.1-like protein 1,Neuronal protein 4.1,4.1N,EPB41L1,KIAA0338,

Tissue Specificity: Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle.

Background: Band 4.1-like protein 1 is a protein that in humans is encoded by the EPB41L1 gene. This gene is mapped to 20q11.23. It is found that a heterozygous missense mutation in the EPB41L1 gene causing nonsyndromic intellectual disability. This gene may function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. What's more, EPB41L1 is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane.

Sequence Similarities: Contains 1 FERM domain.

Molecular Weight: 98 kDa

Gene ID: 2036

UniProt: Q9H4G0