ERV3 antibody (C-Term)

Catalog No. ABIN3042376

This Rabbit Polyclonal antibody specifically detects ERV3 in WB. It exhibits reactivity toward Human.

Quick Overview for ERV3 antibody (C-Term) (ABIN3042376)

Target: ERV3 (ERV3-1) (Endogenous Retrovirus Group 3, Member 1 (ERV3-1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERV3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERV3 Antibody

Binding Specificity: AA 575-604, C-Term

Purpose: Anti-ERV31/ERV3-1 Antibody

Sequence: LELDDEGKVI KEITAKIQKL AHIPVQTWKG

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-ERV31/ERV3-1 Antibody (ABIN3042376). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ERV31.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for ERV3

Target: ERV3 (ERV3-1) (Endogenous Retrovirus Group 3, Member 1 (ERV3-1))

Alternative Name: ERV3-1

Background:

Synonyms: Endogenous retrovirus group 3 member 1 Env polyprotein,ERV-3 envelope protein,ERV3 envelope protein,ERV3-1 envelope protein,Envelope polyprotein,HERV-R envelope protein,ERV-R envelope protein,HERV-R_7q21.2 provirus ancestral Env polyprotein,Surface protein,SU,Transmembrane protein,TM,ERV3-1,ERV3,

Tissue Specificity: Expressed at higher level in adrenal, sebaceous glands and placenta. Expressed at lower level in bone marrow, brain, breast, colon, heart, kidney, liver, lung, ovary, PBL, prostate, skin, spleen, testis, thymus, thyroid, trachea. .

Background: HERV-R_7q21.2 provirus ancestral Env polyprotein, also known as ERV3-1, is a protein that in humans is encoded by the ERV3 gene. By radiation hybrid analysis, the ERV3 gene is mapped to chromosome 7q11.2. The human genome includes many retroelements including the human endogenous retroviruses (HERVs). ERV3, one of the most studied HERVs, is thought to have integrated 30 to 40 million years ago and is present in higher primates with the exception of gorillas. Taken together, the observation of genome conservation, the detection of transcript expression, and the presence of conserved ORFs is circumstantial evidence for a functional role. A functional role is also suggested by the observation that downregulation of ERV3 is reported in choriocarcinoma.

Molecular Weight: 68 kDa

Gene ID: 2086

UniProt: Q14264