FOSL2 antibody (N-Term)

Catalog No. ABIN3042400

This Rabbit Polyclonal antibody specifically detects FOSL2 in WB. It exhibits reactivity toward Human and Rat.

Quick Overview for FOSL2 antibody (N-Term) (ABIN3042400)

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOSL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOSL2 Antibody

Binding Specificity: AA 96-127, N-Term

Purpose: Anti-FRA2/FOSL2 Antibody Picoband®

Sequence: ALPRPGVIKT IGTTVGRRRR DEQLSPEEEE KR

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-FRA2/FOSL2 Antibody Picoband® (ABIN3042400). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human FRA2, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: FOSL2 FOS-like antigen 2". 2. Matsui M, Tokuhara M, Konuma Y et al. (1990). "Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation.". Oncogene 5 (3): 249-55. 3. Molven A, Houge G, Berger R (1997). "Chromosomal assignment of the human gene encoding the Fos-related antigen-2 (FRA2) to chromosome 2p22-p23.". Genomics38 (1): 72-5.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for FOSL2

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Alternative Name: FOSL2

Background:

Synonyms: Fos-related antigen 2,FRA-2,FOSL2,FRA2,

Tissue Specificity: Liver.

Background: Fos-related antigen 2 is a protein that in humans is encoded by the FOSL2 gene. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.

Sequence Similarities: Belongs to the bZIP family. Fos subfamily.

Molecular Weight: 43 kDa

Gene ID: 2355

UniProt: P15408

Pathways: Feeding Behaviour, Photoperiodism